Bioinformatics
Papers to consider:
Teo, S.P. (2021). Review of COVID-19 mRNA Vaccines: BNT162b2 and mRNA-1273. Journal of Pharmacy Practice. Online ahead of print. https://doi.org/10.1177/08971900211009650
Ward, D., Higgins, M., Phelan, J.E., Hibberd, M.L, Campino, S., and Clark, T.G. (2021). An integrated in silico immuno-genetic analytical platform provides insights into COVID-19 serological and vaccine targets. Genome Medicine 13:e4. https://doi.org/10.1186/s13073-020- 00822-6
Assignment: Read the papers of Teo (2021) and Ward et al. (2021) (see first two papers above) and then work through the process below:
Open the COVID Profiler webpage referenced in Ward et al. (2021) using the following link: http://genomics.lshtm.ac.uk/immuno/
Read the Step 1 box and click on the button for the SARS-CoV-2 Immunoanalytics tool + HLA-I Data (warning: it will take quite some time to load the full genome layout with features, but after the loading process has completed, you should see a circular representation of the genome and the associated mapped metadata)
Explore the SARS-COV-2 genome and associated metadata, paying close attention to the pop-up windows that appear as you roll over the genome features especially the links contained therein
Use the tool and information provided in the papers to address the questions below in an essay format (other supplemental information is also provided (see below)
completed your term paper,
Now consider the questions below for this term paper, and address each of these questions in essay format
Questions:
1) What do current serological diagnostics (i.e., COVID-19 tests) target?
2) Are there other potential diagnostic targets available? If so, what are the advantages/disadvantages of this/these over the conventional targets used now (e.g., especially considering the non-synonymous mutation metadata in the SARS-CoV-2 Immunoanalytics tool), and what is/are the functions of this/these target/s?
3) What role do/can modern bioinformatics tools play in vaccine/serological diagnostic development, specifically, and in COVID-19 epidemiology, more generally?
4) How would you characterize the role of bioinformatics in the current pandemic, caused by the SARS-CoV-2 virus and all its mutated variants (e.g., the delta and omicron strains), versus pandemics of the past?
Links for Other Supplemental Information:
CDC: Past Pandemics https://www.cdc.gov/flu/pandemic-resources/basics/past-pandemics.html
CDC: Understanding mRNA COVID-19 Vaccines https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/mrna.html
CDC: What You Need to Know About Variants https://www.cdc.gov/coronavirus/2019-ncov/variants/about-variants.html
Elixir-bio tools: “Everything COVID-19” https://bio.tools/t?page=1&q=COVID-19&sort=score
GIS-AID: Tracking Variants https://www.gisaid.org/hcov19-variants/ (including “3D Structure of Spike with Amino Acid Changes”) John Hopkins: Coronavirus Resource Center https://coronavirus.jhu.edu/map.html
(an image of the Dashboard is provided as a .pdf file in Content/Exams/Final Exam should your browser not be compatible)
PMC: Figure, Single-stranded RNA genome of SARS-CoV-2 https://www.ncbi.nlm.nih.gov/books/NBK554776/figure/article-52171.image.f5/
Science Focus Magazine: Would Spanish flu be as deadly if it occurred today? https://www.sciencefocus.com/science/would-spanish-flu-be-as-deadly-if-it-occurred-today
B
i
oinformatics
Papers to consider:
Teo, S.P. (2021). Review of COVID
–
19 mRNA Vaccines: BNT162b2 and mRNA
–
1273. Journal
of Pharmacy
Practice. Online ahead of print.
https://doi.org/10.1177/08971900211009650
Ward, D., Higgins, M., Phelan, J.E., Hibberd, M.L, Campino, S., and Clark, T.G. (2021). An integrated in
silico immuno
–
genetic analytical platform provides insights into
COVID
–
19 serological and vaccine
targets. Genome Medicine 13:e4.
https://doi.org/10.1186/s13073
–
020
–
00822
–
6
Assignment: Read the papers of Teo (2021) and Ward et al. (2021)
(see
first two papers above)
and then
work through the process below:
·
Open the COVID Profiler webpage referenced in Ward et al. (2021) using the following link:
http://genomics.lshtm.ac.uk/immuno/
·
Read the Step 1 box and click on the button for the SARS
–
CoV
–
2 Immunoanalytics tool + HLA
–
I Data
(warning: it will take quite some time to load the full genome layout with features, but after the loading
process has completed, you should see a circula
r representation of the genome and the associated
mapped metadata)
·
Explore the SARS
–
COV
–
2 genome and associated metadata, paying close attention to the pop
–
up
windows that appear as you roll over the genome features
especially the links contained there
in
·
Use the tool and information provided in the papers to address the questions below in an essay format
(other supplemental information is also provided
(
see below)
·
completed your
term paper
,
Now consider the questions below
for this term paper
, and address each of these questions in essay
format
Questions:
1)
What do current serological diagnostics (i.e., COVID
–
19 tests) target?
2)
Are there other potential diagnostic targets available? If so, what are the
advantages/disadvantages of this/these over the
conventional targets used now (e.g., especially
considering the non
–
synonymous mutation metadata in the SARS
–
CoV
–
2 Immunoanalytics
tool), and what is/are the functions of this/these target/s?
3)
What role do/can modern bioinformatics tools play in vaccine
/serological diagnostic
development, specifically, and in COVID
–
19 epidemiology, more generally?
4)
How would you characterize the role of bioinformatics in the current pandemic, caused by the
SARS
–
CoV
–
2 virus and all its mutated variants (e.g., the delta a
nd omicron strains), versus
pandemics of the past?
Links for Other Supplemental Information:
CDC: Past Pandemics
https://www.cdc.gov/flu/pandemic
–
resources/basics/past
–
pandemics.html
Bioinformatics
Papers to consider:
Teo, S.P. (2021). Review of COVID-19 mRNA Vaccines: BNT162b2 and mRNA-1273. Journal of Pharmacy
Practice. Online ahead of print. https://doi.org/10.1177/08971900211009650
Ward, D., Higgins, M., Phelan, J.E., Hibberd, M.L, Campino, S., and Clark, T.G. (2021). An integrated in
silico immuno-genetic analytical platform provides insights into COVID-19 serological and vaccine
targets. Genome Medicine 13:e4. https://doi.org/10.1186/s13073-020- 00822-6
Assignment: Read the papers of Teo (2021) and Ward et al. (2021) (see first two papers above) and then
work through the process below:
? Open the COVID Profiler webpage referenced in Ward et al. (2021) using the following link:
http://genomics.lshtm.ac.uk/immuno/
? Read the Step 1 box and click on the button for the SARS-CoV-2 Immunoanalytics tool + HLA-I Data
(warning: it will take quite some time to load the full genome layout with features, but after the loading
process has completed, you should see a circular representation of the genome and the associated
mapped metadata)
? Explore the SARS-COV-2 genome and associated metadata, paying close attention to the pop-up
windows that appear as you roll over the genome features especially the links contained therein
? Use the tool and information provided in the papers to address the questions below in an essay format
(other supplemental information is also provided (see below)
? completed your term paper,
Now consider the questions below for this term paper, and address each of these questions in essay
format
Questions:
1) What do current serological diagnostics (i.e., COVID-19 tests) target?
2) Are there other potential diagnostic targets available? If so, what are the
advantages/disadvantages of this/these over the conventional targets used now (e.g., especially
considering the non-synonymous mutation metadata in the SARS-CoV-2 Immunoanalytics
tool), and what is/are the functions of this/these target/s?
3) What role do/can modern bioinformatics tools play in vaccine/serological diagnostic
development, specifically, and in COVID-19 epidemiology, more generally?
4) How would you characterize the role of bioinformatics in the current pandemic, caused by the
SARS-CoV-2 virus and all its mutated variants (e.g., the delta and omicron strains), versus
pandemics of the past?
Links for Other Supplemental Information:
CDC: Past Pandemics https://www.cdc.gov/flu/pandemic-resources/basics/past-pandemics.html
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Home>Biology homework help>write 3 page paper and include all given questions. all guidelines are given in attached document.
Bioinformatics
Papers to consider:
Teo, S.P. (2021). Review of COVID-19 mRNA Vaccines: BNT162b2 and mRNA-1273. Journal of Pharmacy Practice. Online ahead of print. https://doi.org/10.1177/08971900211009650
Ward, D., Higgins, M., Phelan, J.E., Hibberd, M.L, Campino, S., and Clark, T.G. (2021). An integrated in silico immuno-genetic analytical platform provides insights into COVID-19 serological and vaccine targets. Genome Medicine 13:e4. https://doi.org/10.1186/s13073-020- 00822-6
Assignment: Read the papers of Teo (2021) and Ward et al. (2021) (see first two papers above) and then work through the process below:
Open the COVID Profiler webpage referenced in Ward et al. (2021) using the following link: http://genomics.lshtm.ac.uk/immuno/
Read the Step 1 box and click on the button for the SARS-CoV-2 Immunoanalytics tool + HLA-I Data (warning: it will take quite some time to load the full genome layout with features, but after the loading process has completed, you should see a circular representation of the genome and the associated mapped metadata)
Explore the SARS-COV-2 genome and associated metadata, paying close attention to the pop-up windows that appear as you roll over the genome features especially the links contained therein
Use the tool and information provided in the papers to address the questions below in an essay format (other supplemental information is also provided (see below)
completed your term paper,
Now consider the questions below for this term paper, and address each of these questions in essay format
Questions:
1) What do current serological diagnostics (i.e., COVID-19 tests) target?
2) Are there other potential diagnostic targets available? If so, what are the advantages/disadvantages of this/these over the conventional targets used now (e.g., especially considering the non-synonymous mutation metadata in the SARS-CoV-2 Immunoanalytics tool), and what is/are the functions of this/these target/s?
3) What role do/can modern bioinformatics tools play in vaccine/serological diagnostic development, specifically, and in COVID-19 epidemiology, more generally?
4) How would you characterize the role of bioinformatics in the current pandemic, caused by the SARS-CoV-2 virus and all its mutated variants (e.g., the delta and omicron strains), versus pandemics of the past?
Links for Other Supplemental Information:
CDC: Past Pandemics https://www.cdc.gov/flu/pandemic-resources/basics/past-pandemics.html
CDC: Understanding mRNA COVID-19 Vaccines https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/mrna.html
CDC: What You Need to Know About Variants https://www.cdc.gov/coronavirus/2019-ncov/variants/about-variants.html
Elixir-bio tools: “Everything COVID-19” https://bio.tools/t?page=1&q=COVID-19&sort=score
GIS-AID: Tracking Variants https://www.gisaid.org/hcov19-variants/ (including “3D Structure of Spike with Amino Acid Changes”) John Hopkins: Coronavirus Resource Center https://coronavirus.jhu.edu/map.html
(an image of the Dashboard is provided as a .pdf file in Content/Exams/Final Exam should your browser not be compatible)
PMC: Figure, Single-stranded RNA genome of SARS-CoV-2 https://www.ncbi.nlm.nih.gov/books/NBK554776/figure/article-52171.image.f5/
Science Focus Magazine: Would Spanish flu be as deadly if it occurred today? https://www.sciencefocus.com/science/would-spanish-flu-be-as-deadly-if-it-occurred-today
B
i
oinformatics
Papers to consider:
Teo, S.P. (2021). Review of COVID
–
19 mRNA Vaccines: BNT162b2 and mRNA
–
1273. Journal
of Pharmacy
Practice. Online ahead of print.
https://doi.org/10.1177/08971900211009650
Ward, D., Higgins, M., Phelan, J.E., Hibberd, M.L, Campino, S., and Clark, T.G. (2021). An integrated in
silico immuno
–
genetic analytical platform provides insights into
COVID
–
19 serological and vaccine
targets. Genome Medicine 13:e4.
https://doi.org/10.1186/s13073
–
020
–
00822
–
6
Assignment: Read the papers of Teo (2021) and Ward et al. (2021)
(see
first two papers above)
and then
work through the process below:
·
Open the COVID Profiler webpage referenced in Ward et al. (2021) using the following link:
http://genomics.lshtm.ac.uk/immuno/
·
Read the Step 1 box and click on the button for the SARS
–
CoV
–
2 Immunoanalytics tool + HLA
–
I Data
(warning: it will take quite some time to load the full genome layout with features, but after the loading
process has completed, you should see a circula
r representation of the genome and the associated
mapped metadata)
·
Explore the SARS
–
COV
–
2 genome and associated metadata, paying close attention to the pop
–
up
windows that appear as you roll over the genome features
especially the links contained there
in
·
Use the tool and information provided in the papers to address the questions below in an essay format
(other supplemental information is also provided
(
see below)
·
completed your
term paper
,
Now consider the questions below
for this term paper
, and address each of these questions in essay
format
Questions:
1)
What do current serological diagnostics (i.e., COVID
–
19 tests) target?
2)
Are there other potential diagnostic targets available? If so, what are the
advantages/disadvantages of this/these over the
conventional targets used now (e.g., especially
considering the non
–
synonymous mutation metadata in the SARS
–
CoV
–
2 Immunoanalytics
tool), and what is/are the functions of this/these target/s?
3)
What role do/can modern bioinformatics tools play in vaccine
/serological diagnostic
development, specifically, and in COVID
–
19 epidemiology, more generally?
4)
How would you characterize the role of bioinformatics in the current pandemic, caused by the
SARS
–
CoV
–
2 virus and all its mutated variants (e.g., the delta a
nd omicron strains), versus
pandemics of the past?
Links for Other Supplemental Information:
CDC: Past Pandemics
https://www.cdc.gov/flu/pandemic
–
resources/basics/past
–
pandemics.html
Bioinformatics
Papers to consider:
Teo, S.P. (2021). Review of COVID-19 mRNA Vaccines: BNT162b2 and mRNA-1273. Journal of Pharmacy
Practice. Online ahead of print. https://doi.org/10.1177/08971900211009650
Ward, D., Higgins, M., Phelan, J.E., Hibberd, M.L, Campino, S., and Clark, T.G. (2021). An integrated in
silico immuno-genetic analytical platform provides insights into COVID-19 serological and vaccine
targets. Genome Medicine 13:e4. https://doi.org/10.1186/s13073-020- 00822-6
Assignment: Read the papers of Teo (2021) and Ward et al. (2021) (see first two papers above) and then
work through the process below:
? Open the COVID Profiler webpage referenced in Ward et al. (2021) using the following link:
http://genomics.lshtm.ac.uk/immuno/
? Read the Step 1 box and click on the button for the SARS-CoV-2 Immunoanalytics tool + HLA-I Data
(warning: it will take quite some time to load the full genome layout with features, but after the loading
process has completed, you should see a circular representation of the genome and the associated
mapped metadata)
? Explore the SARS-COV-2 genome and associated metadata, paying close attention to the pop-up
windows that appear as you roll over the genome features especially the links contained therein
? Use the tool and information provided in the papers to address the questions below in an essay format
(other supplemental information is also provided (see below)
? completed your term paper,
Now consider the questions below for this term paper, and address each of these questions in essay
format
Questions:
1) What do current serological diagnostics (i.e., COVID-19 tests) target?
2) Are there other potential diagnostic targets available? If so, what are the
advantages/disadvantages of this/these over the conventional targets used now (e.g., especially
considering the non-synonymous mutation metadata in the SARS-CoV-2 Immunoanalytics
tool), and what is/are the functions of this/these target/s?
3) What role do/can modern bioinformatics tools play in vaccine/serological diagnostic
development, specifically, and in COVID-19 epidemiology, more generally?
4) How would you characterize the role of bioinformatics in the current pandemic, caused by the
SARS-CoV-2 virus and all its mutated variants (e.g., the delta and omicron strains), versus
pandemics of the past?
Links for Other Supplemental Information:
CDC: Past Pandemics https://www.cdc.gov/flu/pandemic-resources/basics/past-pandemics.html
Applied Sciences
Architecture and Design
Biology
Business & Finance
Chemistry
Computer Science
Geography
Geology
Education
Engineering
English
Environmental science
Spanish
Government
History
Human Resource Management
Information Systems
Law
Literature
Mathematics
Nursing
Physics
Political Science
Psychology
Reading
Science
Social Science
Liberty University
New Hampshire University
Strayer University
University Of Phoenix
Walden University
Home
Homework Answers
Blog
Archive
Tags
Reviews
Contact
twitterfacebook
Copyright © 2022 SweetStudy.com
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